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Penicillin-specific stimulation of lymphocytes from hypersensitive patients. A, positive responses were observed by stimulation of peripheral blood mononuclear cells from penicillin allergic patient 1 (P1) and patient 2 (P2) with BP and PA. B, epitope profile of synthetic BP-HSA conjugate and normalized PA-HSA conjugate generated in vitro. C, proliferation of lymphocytes with synthetic conjugate. RPMI medium supplemented with 10% HSA was used as control (R9).
