Table 1.
Data | Pre-ECMO | Day 1 | Day 2 | Day 3 | Day 4 | Day 18 |
Mechanical ventilation | ||||||
Ventilatory mode | VCV ∥ | PSV ∥ | PSV ∥ | PSV ∥ | PSV ∥ | PSV ∥ |
Peak pressure (min – max) - cm H2O | 28 - 28 | 28 - 33 | 28 - 33 | 28 - 28 | 26 - 28 | 24 - 24 |
PEEP (min – max) - cm H2O £ | 20 – 20 | 20 – 25 | 20 - 25 | 20 - 20 | 18 - 20 | 10 – 10 |
FIO2 (min – max) ¥ | 0.6 – 0.7 | 0.7 – 0.7 | 0.6 – 0.7 | 0.6 – 0.6 | 0.6 – 0.6 | 0.6 – 0.6 |
Respiratory rate (min – max) - breaths/min | 22 - 30 | 25 - 36 | 18 - 34 | 22 - 39 | 24 – 36 | 22 - 38 |
ECMO € | ||||||
Blood flow (min – max) - L/min | 6.0 – 6.5 | 6.0 – 6.0 | 5.5 – 6.0 | 5.0 – 5.5 | 5.0 – 5.0 | 5.0 – 5.0 |
Sweeper flow (min – max) - L/min | 6.0 – 10.0 | 6.0 – 6.0 | 4.0 – 6.0 | 2.5 – 4.0 | 2.5 – 2.5 | 2.5 – 2.5 |
FIO2 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
Routine blood gas | ||||||
PaO2 - mm Hg | 42 | 50 | 62 | 74 | 55 | 81 |
PaCO2 - mm Hg | 118 | 51 | 38 | 53 | 51 | 51 |
SBE - mEq/L * | 1.8 | 6.1 | -1.0 | 0.9 | -0.8 | 2.1 |
pH | 7.10 | 7.41 | 7.43 | 7.33 | 7.32 | 7.36 |
Patient data | ||||||
RASS (min – max) | -1 - 0 | 0 - 0 | 0 – 0 | 0 – 0 | 0 – 0 | -5 - 0 |
Lung injury score ¶ | 4.00 | 4.00 | 4.00 | 3.75 | 3.75 | 3.00 |
Total SOFA score § | 10 | 9 | 6 | 4 | 4 | 4 |
Respiratory SOFA | 4 | 4 | 4 | 4 | 4 | 4 |
Cardiovascular SOFA | 3 | 3 | 0 | 0 | 0 | 0 |
Hematological SOFA | 1 | 1 | 1 | 0 | 0 | 0 |
Hepatic SOFA | 1 | 0 | 0 | 0 | 0 | 0 |
Neurological SOFA | 0 | 0 | 0 | 0 | 0 | 0 |
Renal SOFA | 1 | 1 | 1 | 0 | 0 | 0 |
SBE denotes standard base excess.
# RASS denotes Richmond agitation sedation score.
SOFA denotes sequential organ failure assessment. This is a score to diagnose and quantify organ failure, which ranges from 0 to 24.
¶ The lung injury score is Murray`s score, which quantifies the severity of lung injury based on the respiratory compliance, PEEP, number of quadrants of chest X-ray infiltrated and PaO2/FIO2 ratio.
∥ VCV denotes volume-controlled ventilation.
∥ PSV denotes pressure-support ventilation.
£ PEEP denotes positive end-expiratory pressure.
¥ FiO2 denotes inspiratory fraction of oxygen.
€ ECMO denotes extracorporeal membrane oxygenation.