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. 2011 Jun 28;123(1):58–70. doi: 10.1093/toxsci/kfr164

TABLE 3.

Redox Values in Epithelia and Plasma after 7 Days of Exposure to SDD

SDD (mg/l) GSH (nmol/mg) GSSG (nmol/mg) GSH/GSSG ΔE (mV)a
Average SEM Average SEM Average SEM Average SEM
Oral mucosa
    0 43.23 2.47 4.40 0.22 9.92 0.73 −206.97 1.62
    0.3 45.12 5.07 5.12 0.52 8.82 0.60 −205.68 2.35
    4 44.75 1.84 4.53 0.25 9.97 0.56 −207.60 1.12
    14 47.02 5.41 5.37 0.62 8.77 0.38 −206.24 1.87
    60 43.17 5.13 4.90 0.56 8.79 0.15 −205.06 2.06
    170 46.34 5.63 5.67 0.80 8.26b 0.19 −205.29 1.35
    520 46.38 4.57 5.88b 0.46 7.88c 0.32 −204.78 1.59
Duodenum
    0 16.77 1.26 0.24 0.03 71.33 5.15 −220.58 1.36
    0.3 17.57 1.25 0.30 0.03 59.99 6.85 −218.77 2.03
    4 16.99 0.73 0.30 0.01 57.33 0.49 −218.11 0.56
    14 16.75 0.94 0.31 0.01 53.41 2.69 −216.86 1.44
    60 17.61 1.08 0.36b 0.01 48.47b 2.00 −216.24 1.36
    170 18.92 1.49 0.43c 0.01 44.28c 2.72 −215.89 b 1.77
    520 19.98 1.32 0.48c 0.02 41.23c 1.86 −215.75b 1.37
Jejunum
    0 15.30 0.74 0.34 0.02 45.29 2.11 −213.49 1.08
    0.3 14.14 0.95 0.37 0.01 38.43 1.68 −210.20 1.39
    4 13.63 0.48 0.33 0.02 41.12 1.66 −210.70 0.58
    14 12.09 0.36 0.36 0.02 34.51d 2.30 −206.68 1.05
    60 14.25 0.99 0.32 0.01 45.51 5.25 −212.28 2.29
    170 11.47c 0.23 0.29 0.01 40.37 1.86 −208.15c 0.71
    520 12.79b 0.45 0.33 0.01 38.72 1.54 −209.05b 0.98
Plasma GSH (μM) GSSG (μM)
    0 25.45 0.74 3.59 0.35 7.34 0.65 −137.40 1.26
    0.3 24.86 0.55 4.18 0.27 6.05 0.46 −134.59 1.17
    4 27.69 1.53 4.20 0.33 6.84 0.92 −137.35 2.17
    14 26.91 1.45 4.04 0.32 6.92 0.83 −137.10 2.44
    60 32.45c 1.37 4.18 0.23 7.93 0.81 −141.62 1.80
    170 30.41b 1.09 4.85b 0.23 6.35 0.45 −137.90 1.46
    520 31.46b 1.82 5.07c 0.23 6.28 0.53 −138.12 1.84
a

See “MATERIALS AND METHODS” for calculation.

b

Statistically significant from control by Shirley’s tests (p < 0.05).

c

Statistically significant from control by Shirley’s tests (p < 0.01).

d

Statistically significant from control by Dunn’s tests (p < 0.01).