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. 2011 Sep 1;22(17):3263–3275. doi: 10.1091/mbc.E11-01-0020

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© 2011 Giang Ho et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 11: — PC-3 cell migration is inhibited by the up-regulation of RhoA independent of the repression of RhoC expression. Confluent monolayers of PC-3/TR/RhoA (A), PC-3/TR/RhoC (B), or PC-3/TR/RhoAR68E (C) cells were scratched and treated (+dox) or not (−dox) with 100 ng/ml doxycycline. Phase-contrast microscopy photographs were taken immediately after wounding (0 h) and 48 h after wounding (48 h). Right, quantification of wound closure. The results are expressed as mean ± SD of at least four independent experiments. Bar, 250 μm. ***p < 0.001, ANOVA, followed by Tukey–Kramer analysis.