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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: J Cell Biochem. 2008 Aug 15;104(6):2228–2240. doi: 10.1002/jcb.21779

Fig. 4.

Fig. 4

Quantification of the increased DSS sensitivity in Mtgr1/p19ARF double-null mice. A. Double-null mice lose a larger percent of their initial body weight than the other genotypes when treated with DSS. For simplicity, only the double-null control group is shown here, but the mock treated mice all behaved similarly (N = 8 per group). B. Colon lengths were also significantly reduced in the DSS-treated double-null mice when compared to DSS-treated wild-type mice (P = 0.0307). Only the double-null control group is shown here, but the mock treated mice all behaved similarly (N = 8 per group). C. Using the Dieleman colitis grading system, sections were blindly graded. Genotypes are as follows: WT, wild-type; AN, p19ARF-null; MN, Mtgr1-null, DN, double-null. The double-null group displayed significantly more damage than the control group (P = 0.0051).