Figure 1.
Pedigrees of the eight kindreds. Triangles represent individuals, shaded triangles represent affected individuals. Triangles with diagonal lines through them represent deceased individuals. The proband is indicated by a shaded arrowhead. Individuals with a confirmed progranulin mutation are indicated by an asterisk. An arrow pointing to the right in a sibship represents additional unaffected persons, but they were purposefully excluded to maintain confidentiality.