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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: Dev Biol. 2011 Jul 14;357(2):347–355. doi: 10.1016/j.ydbio.2011.07.011

Figure 2. atRAL supplementation rescues Rdh10trex mutants to birth.

Figure 2

Pregnant females were supplemented with atRAL by oral gavage every 12 hours as described in material and methods, beginning at E7.25 and extending up until birth. (A and B) Pups were collected and photographed directly after birth. (C–F) H&E stained transverse sections through the lung tissue are shown at 10X (C and D) and 40X (E and F) magnification. Note the expanded lung tissue morphology, indicative of lung inflation, in the Rdh10+/trex pup. In contrast, the Rdh10trex/trex lung tissue remains condensed.