Table 2.
Clinicopathological factors and their relationship to the expression of different proteins, assessed in AC cases
| Characteristics | CD44s (n = 77) | COX-2 (n = 82) | ||
|---|---|---|---|---|
| Low(%) | High(%) | Low(%) | High(%) | |
| Tumor differentiation | ||||
| Well, | 7(33.3) | 14(66.7) | 7(31.8) | 15(68.2) |
| Moderately, poorly | 29(51.8) | 27(48.2) | 9(15.0) | 51(85.0) |
| p-value | 0.117 | 0.085 | ||
| Tumor size | ||||
| < 3 cm | 12(42.9) | 16(57.1) | 1(3.4) | 28(96.6) |
| ≥ 3 cm | 24(50.0) | 24(50.0) | 14(26.9) | 38(73.1) |
| p-value | 0.547 | 0.009 | ||
| Lymph node metastasis | ||||
| N0-1 | 33(53.2) | 29(46.8) | 14(20.9) | 539(79.1) |
| N2-3 | 3(20.0) | 12(80.0) | 2(13.3) | 13(86.7) |
| p-value | 0.021 | 0.397 | ||
| Stage | ||||
| I | 20(48.8) | 21(51.2) | 10(23.3) | 33(76.7) |
| II | 8(53.3) | 7(46.7) | 3(16.7) | 15(83.3) |
| III | 8(38.1) | 13(61.9) | 3(14.3) | 18(85.7) |
| p-value | 0.616 | 0.373 | ||
| Lymphatic invasion | ||||
| Negative | 19(42.2) | 26(57.8) | 11(23.4) | 36(76.6) |
| Positive | 16(53.3) | 14(46.7) | 5(15.2) | 28(84.8) |
| p-value | 0.345 | 0.364 | ||
AC, adenocarcinoma; COX, cyclooxygenase.