Table 3.
Clinicopathological factors and their relationship to the expression of different proteins, assessed in SCC cases
| Characteristics | CD44s (n = 72) | COX-2 (n = 77) | ||
|---|---|---|---|---|
| Low(%) | High(%) | Low(%) | High(%) | |
| Tumor differentiation | ||||
| Well | 0(0) | 4(100) | 1(25.0) | 3(75.0) |
| Moderately, poorly | 6(8.8) | 62(91.2) | 22(30.1) | 51(69.9) |
| p-value | 0.701 | 0.655 | ||
| Tumor size | ||||
| ≤ 3 cm | 1(5.6) | 17(94.4) | 6(30.0) | 14(70.0) |
| > 3 cm | 4(7.5) | 497(92.5) | 20(37.7) | 33(62.3) |
| p-value | 0.625 | 0.976 | ||
| Lymph node metastasis | ||||
| N0-1 | 5(8.1) | 57(91.9) | 21(31.3) | 46(68.7) |
| N2-3 | 1(10.0) | 9(90.0) | 2(20.0) | 8(80.0) |
| p-value | 0.607 | 0.373 | ||
| Stage | ||||
| I | 3(7.9) | 35(92.1) | 12(28.6) | 30(71.4) |
| II | 1(6.3) | 15(93.8) | 4(23.5) | 13(76.5) |
| III | 2(11.1) | 16(88.9) | 7(38.9) | 11(61.1) |
| p-value | 0.736 | 0.594 | ||
| Lymphatic invasion | ||||
| negative | 5(13.2) | 33(86.8) | 11(27.5) | 29(72.5) |
| positive | 1(3.3) | 29(96.7) | 11(33.3) | 22(66.7) |
| p-value | 0.163 | 0.589 | ||
SCC, squamous cell carcinoma; COX, cyclooxygenase.