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Ectopic expression of ODC in ski-deficient embryos. Frontal sections were prepared from c-ski heterozygous and homozygous mutant embryos at 9.5 dpc, and analyzed with the TUNEL assay (a,b). Apoptotic cells in the neuroepithelium that had incorporated labeled dUTP are indicated by arrows. The signals of in situ hybridization (c,d) or immunostaining for ODC (e,f) are shown. Cells that overexpressed ODC are indicated by arrows.
