Figure 1. Sox10 is rapidly downregulated in differentiating melanocytes.

A–D) Sox10 positive (A,B) and Sox10 negative (C,D) melanocytes from 33 hpf embryo are indicated by arrows. Non-pigmented cells expressing Sox10 are indicated (*). E) sox10 in situ hybridisation on 33 hpf embryo showing both sox10 positive (arrowhead) and sox10 negative (arrow) melanocytes. F) Time-course of percentage of melanocytes showing Sox10 or sox10 expression during melanocyte differentiation stages. Expression was examined in 20 pigmented cells from each of 5 fish (i.e. n = 100) at each time point.