Table 3. Functional annotation of genes identified by two-factor ANOVA.

Functional Category	Genes in the Function ( 10% FDR)
GOCC Chromatin remodelling complex (disease factor)	APPL1, ARID1A, ARID1B, CHD4, CIR1, HDAC4, HDAC7, HDAC9, MBD2, MTA1, PHF21A, RSF1, SIN3A, SIRT2, SIRT3, SMARCA4, SMARCB1, SNARCE1, SUDS3, TBL1XR1
GOCC histone deacetylase complex (exercise factor)	APPL2, CHD3, CHD4, GATAD2A, HDAC1, HDAC11, HDAC3, HDAC4, HDAC5, LOC642954, MBD3, NRIP1, RBBP4, RBBP7, RERE, SAP18, TAL1, TBL1XR1

Functional enrichment of genes that are significantly differentially expressed in both disease and training.