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. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: J Med Chem. 2006 Jan 12;49(1):27–30. doi: 10.1021/jm050892j

Table 2.

Inhibitory activity and Test Set Data for the 3D QSAR studies

			pIC₅₀

#	Structure	IC₅₀	Obs	Pred
21		1.3 µM	5.89	5.30
22		2.1 µM	5.68	5.61
23		1.2 µM	5.92	5.61
24		2.3 µM	5.64	5.32
25		4.4 µM	5.36	5.34
26		16.6 µM	4.78	4.94
27		22.4 µM	4.65	4.33
28		5.6 µM	5.25	4.97
29		3.0 µM	5.52	5.33
30		0.5 µM	6.30	6.27