Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A two-stroke model for transcriptional activation by ER and p300. In this model ER and p300 function cooperatively to increase productive transcription initiation in the first stroke, whereas ER promotes the reassembly of the transcription preinitiation complex in the second stroke.
