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. Author manuscript; available in PMC: 2012 Sep 7.
Published in final edited form as: J Am Chem Soc. 2011 Aug 12;133(35):14042–14053. doi: 10.1021/ja2046167

Figure 4.

Figure 4

Calculated major solution conformers ad. Overlay of these conformations (e) shows the conserved ABEF ring conformations where syn pentane interactions (f) are important in fixing the relative conformations of E and F rings.