Table 1c.
Baseline pulmonary function, BAL and serum data of asthmatic and control participants*
| control | asthma | Unadjusted p | Adjusted p† | |
|---|---|---|---|---|
| n | 21 | 23 | ||
| FEV1 (% predicted) | 95.9 ± 7.3 | 82.4 ± 14.1 | < 0.001 | 0.004 |
| FVC (% predicted) | 93.6 ± 8.4 | 84.1 ± 12.9 | 0.01 | 0.04 |
| FEV/FVC (% predicted) | 102.7 ± 5.5 | 98.8 ± 14.3 | 0.02 | 0.36 |
| FEV1/FVC (absolute) | 82.6 ± 4.79 | 79.6 ± 11.3 | 0.26 | 0.24 |
| BAL macrophages (%)‡ | 85.2 ± 12.7 | 93.0 ± 4.1 | < 0.05 | 0.08 |
| BAL lymphocytes (%)‡ | 8.0 ± 9.1 | 3.5 ± 2.6 | 0.01 | 0.03 |
| BAL neutrophils (%)‡ | 6.7 ± 10.1 | 3.1 ± 3.4 | 0.6 | 0.66 |
| BAL eosinophils (%)‡ | 0.02 ± 0.11 | 0.51 ± 0.75 | 0.1 | 0.07 |
| BAL leptin (pg/ml)‡ | 23.9 ± 28.4 | 35.3 ± 65.4 | 0.99 | 0.27 |
| BAL adiponectin (pg/ml)‡ | 2502 ± 2350 | 1527 ± 1313 | 0.09 | 0.67 |
| Serum IgE (IU/ml) | 45.7 ± 72.4 | 133.3 ± 172.2 | 0.02 | 0.11 |
| Serum leptin (ng/ml) | 26.6 ± 19.2 | 30.2 ± 30.5 | 0.77 | 0.70 |
| Serum adiponectin (μg/ml) | 36.3 ± 65.9 | 13.8 ± 10.5 | 0.12 | 0.15 |
*
Values shown are mean and standard deviation. p values shown for T- test for continuous variables except for BAL eosinophils, where p value is shown for Kruskal Wallis test.
†
p value comparing control and asthmatic, adjusted for BMI.
FEV1, FVC and FEV1/FVC are % predicted from Hankinson,48.
BAL is bronchoalveolar lavage.
‡
n=21 for asthmatics and 21 for controls