Table 1.
Subject demographics, electrophysiology, and clinical results.
| ILBD versus | ||||||
|---|---|---|---|---|---|---|
| Overall | PD | Control | ||||
| PD | ILBD | Control | P | P | P | |
| N | 7 | 10 | 28 | |||
| Age at EEG (y); mean (SD) | 81.3 (4.9) | 89.4 (4.4) | 86.3 (5.4) | .01 | .003* | .11 |
| Female | 4 (57%) | 3 (30%) | 14 (50%) | .20 | .35 | .46 |
| Rest EMG Discharge | 4 (57%) | 3 (30%) | 4 (14%) | .05 | .35 | .35 |
| Rest EMG Discharge Peak Frequency (Hz); mean (SD) | 4.09 (0.61) | 4.07 (0.74) | 8.1 (2.3) | .009 | .99 | .008* |
| Rest EMG Discharge Peak Frequency <5.5 Hz | 4/4 (100%) | 3/3 (100%) | 0/4 (0%) | .004 | >.99 | .03* |
| Activation EMG Discharge | 7 (100%) | 4 (40%) | 17 (61%) | .04 | .03* | .29 |
| Activation EMG Discharge Peak Frequency (Hz); mean (SD) | 8.2 (3.5) | 11.2 (3.1) | 9.3 (3.9) | .44 | .20 | .37 |
| Rest or Activation EMG discharge | 7 (100%) | 7 (70%) | 18 (64%) | .18 | .10 | >.99 |
| Background Rhythm Frequency (Hz); mean (SD) | 7.25 (0.67) | 8.32 (0.80) | 9.40 (0.83) | <.001 | .01* | .001* |
| Adjusted for Age and Sex; adjusted mean | 7.0 | 8.5 | 9.4 | <.001 | .001* | .004* |
| Delta BP(%); mean (SD) | 15.3 (5.9) | 18 (11) | 14.7 (7.5) | .62 | .56 | .33 |
| Theta BP(%); mean (SD) | 37 (14) | 18.4 (7.9) | 19 (12) | .002 | .002* | .88 |
| Alpha BP(%); mean (SD) | 29 (11) | 34 (15) | 41 (13) | .07 | .44 | .15 |
| Beta BP(%); mean (SD) | 19.2 (8.2) | 29 (11) | 25 (11) | .22 | .09 | .39 |
| UPDRS III; mean (SD) | 30 (15), 5 | 9.2 (3.5) | 8.0 (5.4) | <.001 | <.001 | .62 |
| MMSE; mean (SD) | 28.33 (0.82) | 27.9 (1.3) | 28.6 (1.5) | .48 | .55 | .23 |
| AVLT A7; mean (SD) | 5.4 (2.7) | 7.9 (3.6) | 7.8 (4.0) | .43 | .28 | .98 |
| Stroop Interference; mean (SD) | −9.7 (9.9) | −6.3 (4.5) | −6.5 (6.6) | .64 | .44 | .95 |
| COWA; mean (SD) | 44.2 (9.0) | 29 (11) | 40 (12) | .06 | .03 | .04 |
| JLO; mean (SD) | 17.0 (5.6) | 20.9 (4.0) | 24.0 (4.1) | .03 | .20 | .12 |
| TMT-B; mean (SD) | 198 (79) | 209 (63) | 116 (57) | .002 | .76 | .002 |
ILBD=Incidental Lewy body disease; PD=Parkinson's disease without dementia. Rest EMG Discharge=rhythmic EMG discharges at rest; Activation EMG Discharge=rhythmic EMG modulation during postural muscle activation. BP=EEG bandpower.
*
Significant P values