Fig 1.

GBM sample classification and comparison of cell line models using a subset of common genes between two array platforms (n = 3322). (A) Identification of three major cluster groups of GBM patient samples by hierarchical agglomerative cluster analysis. The dendrogram was created using 1-correlation distance metric and average linkage measure. (B–D) Scatterplots comparing U251 (x-axis) and U87 (y-axis) gene expression of cell grown in vitro (B) and in vivo as sc (C) and ic (D) tumours in mice. Pearson correlation coefficients were calculated for each comparison and listed in each plot.