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. Author manuscript; available in PMC: 2012 Sep 7.
Published in final edited form as: J Am Chem Soc. 2011 Aug 16;133(35):13984–14001. doi: 10.1021/ja203733q

Figure 13.

Figure 13

Postulated catalytic cycles accounting for the results of the kinetic studies on the CuAAC reactions in Scheme 1 in CD3CN (A) and CH3OH (B). L: copper-binding ligand or the counter ion. py: 2-pyridyl. Blue, orange, and purple represents the +2, +1, and +3 oxidation states of copper, respectively. The steps of copper(I) triazolide protonation are in green.