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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Comp Biochem Physiol C Toxicol Pharmacol. 2011 Mar 30;155(1):64–70. doi: 10.1016/j.cbpc.2011.03.007

Figure 1.

Figure 1

The Sp-couchianus backcross hybrid breeding scheme. An F1 hybrid is produced by mating a non-spotted male X. couchianus (+/+) with a female X. maculatus that has the X-linked spot-sided pattern (Sp/Sp; termed Jp 163B strain). The female F1 hybrids (Sp/+) are subsequently back-crossed to the parental X. couchianus male (+/+). This breeding scheme produces first generation backcross progeny that are either Sp (Sp/+) pigmented or wild-type (+/+). These wildtype fish are discarded because they lack the Xmrk oncogene.