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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Surgery. 2011 Sep;150(3):429–435. doi: 10.1016/j.surg.2011.07.001

Figure 2.

Figure 2

Figure 2

Sprouting of HUVEC spheroid in collagen gels. After 24 h of treatment with HDAC inhibitor, spheroid sprouting was analyzed. (Control) Low baseline sprouting was observed. (VEGF) in the presence of VEGF, the sprouting increased significantly (2B). Increasing of HUVEC sprouting in VPA (VPA) or SAHA (SAHA) alone groups were not significant (2B). Treatment of VEGF combined VPA (VEGF + VPA) or SAHA (VEGF + SAHA) greatly enhanced the HUVECs sprouting (2B). ** p < 0.01.