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. Author manuscript; available in PMC: 2011 Sep 2.
Published in final edited form as: Chem Biol. 2007 Jul;14(7):764–774. doi: 10.1016/j.chembiol.2007.05.010

Figure 1.

Figure 1

Structures of the Inhibitors for Methionine Aminopeptidases.

Bengamide A and LAF 389 are non-selective inhibitors for both MetAP1 and MetAP2. Fumagillin, ovalicin and TNP-470 are human MetAP2-specific inhibitors. IV-43 is a human MetAP1-specific inhibitor.