Figure 3. Inhibition of NF-κB causes an increase in intracellular ROS in cells expressing BCR-ABL.
(A) 32D/p185 cell were incubated with DMSO (vehicle control) or 1μM Imatinib or Compound A for 16 hours without or (B) with antioxidants. Cells were then incubated with DCF-DA and fluorescence was measured my FACS analysis.