Skip to main content
. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Biometrics. 2011 Jan 31;67(3):975–986. doi: 10.1111/j.1541-0420.2010.01544.x

Table 3.

Empirical power when h(Z) is linear at the type I error rate of 0.05 with p=5, 10, and 100 genes are used to fit the model while the true number of genes is 5. Testing was performed based on (i) sup-statistic with the original kernel (subscript S^); (ii) sup-statistic with the kernel PCA including 90% of eigenvalues (subscript S~); (iii) score test with ρ fixed at ρ2 (upper bound of I) with original kernel (subscript Q^); (iv) score test at ρ2 with kernel PCA (subscript Q~). The null distributions were generated based on the resampling procedure (indexed by P).

p = 5 p = 10 p = 100
Censoring % 50% 25% 50% 25% 50% 25%
Kernel n 100 200 100 200 100 200 100 200 100 200 100 200
Correlation = 0.5
Gaussian sup PS^ 67 94 83 99 68 94 83 99 67 92 82 98
PS~ 68 94 85 99 69 94 85 99 68 92 83 99

ρ 2 PQ^ 69 95 86 99 69 94 84 100 67 92 82 98
PQ~ 72 96 88 99 71 94 86 100 69 92 84 99

Linear PQ^ 74 97 88 100 71 96 86 100 66 94 81 99
PQ~ 75 96 88 100 72 96 87 100 66 94 81 99

Correlation = 0.2
Gaussian sup PS^ 42 72 57 89 37 66 49 83 28 57 37 73
PS~ 49 78 65 92 42 70 56 86 34 61 48 76

ρ 2 PQ^ 43 74 59 90 38 67 50 84 28 57 37 73
PQ~ 54 82 69 94 45 72 60 87 34 62 48 76

Linear PQ^ 44 77 59 89 39 69 54 86 29 58 39 73
PQ~ 44 78 61 90 40 70 54 86 30 58 40 74