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. Author manuscript; available in PMC: 2012 Jun 15.
Published in final edited form as: Oncogene. 2011 May 30;30(50):4990–4998. doi: 10.1038/onc.2011.205

Figure 4. Prostate cell proliferation and apoptosis in TK+/+ TRAMP+ and TK−/− TRAMP+ mice.

Figure 4

A, BrdU immunostaining was performed on prostates from 30-week TK+/+ TRAMP+ and TK−/− TRAMP+ mice. B, Detection of TUNEL positive cells in prostate tissue of TK+/+ TRAMP+ and TK−/− TRAMP+ mice at 30-weeks of age. C, Prostates from 30-week-old TK+/+ TRAMP+ and TK−/− TRAMP+ mice did not exhibit differences in BrdU staining but did contain significant differences in the extent of TUNEL positive cell staining. Data are expressed as means ± SE. Five separate areas were counted from four independent specimens per group, and representative images are shown. *p<0.05 compared to TK+/+ TRAMP+ group. Arrows depict a few of the positive staining cells.