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. 2010 Oct 21;1(1):85–97.

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Fiugre 1 — Gene set enrichment analysis (GSEA) for the JAK-STAT signaling pathway. (A) Shown are enrichment scores with a ranked list metric. The arrow indicates the enrichment score of 0.45. (B) Heat map of the results of microarray analysis of 32 core enrichment genes in the JAK-STAT signaling pathway in wild type (Klf4^+/+) and Klf4-null (Klf4^-/-) MEFs in triplicate. Red color represents up-regulated and blue color, down-regulated, genes. Significantly enriched data sets are selected according to GSEA default settings, i.e., P < 0.001 and a false discovery rate (FDR) < 0.