Table S4.
Gene sets Identified by GSEA
| Specific genes enriched in Klf4-null MEFs | |||
|---|---|---|---|
| NAME | PROBE | RUNNING ES | CORE ENRICHMENT |
| BILE_ACID_BIOSYNTHESIS | |||
| row_17 | AKR1D1 | -0.492 | Yes |
| row_18 | SOAT2 | -0.471 | Yes |
| row_19 | ALDH2 | -0.405 | Yes |
| row_20 | ADH7 | 0.001 | Yes |
| ZUCCHI_EPITHELIAL_DN | |||
| row_18 | STRN4 | -0.597 | Yes |
| row_19 | PPM1G | -0.591 | Yes |
| row_20 | PDLIM1 | -0.550 | Yes |
| row_21 | ANXA1 | -0.480 | Yes |
| row_22 | PICALM | -0.363 | Yes |
| row_23 | CXCL1 | -0.195 | Yes |
| row_24 | AREG | 0.001 | Yes |
| CROONQUIST_IL6_RAS_U | |||
| row_17 | CCL4 | -0.468 | Yes |
| row_18 | CCL5 | 0.001 | Yes |
| HSA04640_HEMATOPOIETIC_CELL_LINEAGE | |||
| row_57 | ITGA6 | -0.469 | Yes |
| row_58 | CSF1 | -0.461 | Yes |
| row_59 | CD9 | -0.459 | Yes |
| row_60 | CD44 | -0.392 | Yes |
| row_61 | CD34 | -0.310 | Yes |
| row_62 | ITGA5 | -0.222 | Yes |
| row_63 | CD14 | -0.123 | Yes |
| row_64 | ITGA3 | 0.005 | Yes |
| BCRPATHWAY | |||
| row_25 | VAV1 | -0.508 | Yes |
| row_26 | BTK | -0.507 | Yes |
| row_27 | RAC1 | -0.484 | Yes |
| row_28 | MAPK3 | -0.476 | Yes |
| row_29 | CALM2 | -0.433 | Yes |
| row_30 | JUN | -0.387 | Yes |
| row_31 | PPP3CA | -0.335 | Yes |
| row_32 | BLNK | 0.001 | Yes |
| LEE_MYC_E2F1_DN | |||
| row_44 | ABCD3 | -0.489 | Yes |
| row_45 | IGF1 | -0.479 | Yes |
| row_46 | G0S2 | -0.481 | Yes |
| row_47 | CYP7B1 | -0.460 | Yes |
| row_48 | MCM10 | -0.440 | Yes |
| *** | |||
| row_49 | PXMP2 | -0.421 | Yes |
| row_50 | ELOVL5 | -0.396 | Yes |
| row_51 | RGS16 | -0.326 | Yes |
| row_52 | EGFR | -0.206 | Yes |
| row_53 | NETO2 | 0.001 | Yes |
| HSA04012_ERBB_SIGNALING_PATHWAY | |||
| row_67 | EREG | -0.415 | Yes |
| row_68 | ERBB2 | -0.408 | Yes |
| row_69 | CAMK2B | -0.410 | Yes |
| row_70 | AKT2 | -0.402 | Yes |
| row_71 | MAP2K4 | -0.386 | Yes |
| row_72 | MAPK3 | -0.373 | Yes |
| row_73 | PAK3 | -0.357 | Yes |
| row_74 | EIF4EBP1 | -0.344 | Yes |
| row_75 | JUN | -0.328 | Yes |
| row_76 | SRC | -0.310 | Yes |
| row_77 | ARAF | -0.304 | Yes |
| row_78 | PAK1 | -0.269 | Yes |
| row_79 | HBEGF | -0.209 | Yes |
| row_80 | EGFR | -0.137 | Yes |
| row_81 | AREG | 0.000 | Yes |
| ZHAN_PCS_MULTIPLE_MYELOMA_SPKD | |||
| row_16 | IFIT3 | -0.671 | Yes |
| row_17 | CTGF | -0.614 | Yes |
| row_18 | LGALS3BP | -0.484 | Yes |
| row_19 | TSPAN7 | -0.257 | Yes |
| row_20 | AREG | 0.000 | Yes |
| HSA04140_REGULATION_OF_AUTOPHAGY | |||
| row_18 | PRKAA1 | -0.532 | Yes |
| row_19 | ULK2 | -0.509 | Yes |
| row_20 | GABARAPL1 | -0.463 | Yes |
| row_21 | PIK3R4 | -0.389 | Yes |
| row_22 | ATG3 | 0.005 | Yes |
| HSA04940_TYPE_I_DIABETES_MELLITUS | |||
| row_15 | CPE | -0.377 | Yes |
| row_16 | FAS | -0.360 | Yes |
| row_17 | HSPD1 | -0.336 | Yes |
| row_18 | ICA1 | 0.007 | Yes |
| POMEROY_DESMOPLASIC_VS_CLASSIC_MD_DN | |||
| row_31 | NUCB1 | -0.430 | Yes |
| row_32 | SFRS2IP | -0.404 | Yes |
| row_33 | PSMB5 | -0.347 | Yes |
| row_34 | CRABP2 | 0.000 | Yes |
| LEE_MYC_TGFA_DN | |||
| row_45 | G0S2 | -0.535 | Yes |
| row_46 | CYP7B1 | -0.516 | Yes |
| row_47 | MCM10 | -0.500 | Yes |
| row_48 | PXMP2 | -0.484 | Yes |
| row_49 | ELOVL5 | -0.464 | Yes |
| row_50 | RGS16 | -0.404 | Yes |
| row_51 | EGFR | -0.298 | Yes |
| row_52 | PTP4A3 | -0.184 | Yes |
| row_53 | NETO2 | 0.001 | Yes |
| HSA00760_NICOTINATE_AND_NICOTINAMIDE_METABOLISM | |||
| row_17 | NT5C2 | -0.620 | Yes |
| row_18 | NNMT | -0.478 | Yes |
| row_19 | ENPP1 | -0.242 | Yes |
| row_20 | NT5E | 0.007 | Yes |
| CELL_MOTILITY | |||
| row_36 | FLNA | -0.457 | Yes |
| row_37 | BCL9L | -0.451 | Yes |
| row_38 | ACTN4 | -0.429 | Yes |
| row_39 | MSN | -0.411 | Yes |
| row_40 | F2R | -0.383 | Yes |
| row_41 | THBS1 | -0.353 | Yes |
| row_42 | F11R | -0.330 | Yes |
| row_43 | ANXA1 | -0.293 | Yes |
| row_44 | CTGF | -0.250 | Yes |
| row_45 | CXCL10 | -0.194 | Yes |
| row_46 | ENPP2 | -0.109 | Yes |
| row_47 | CCL5 | 0.002 | Yes |
| TYROSINE_METABOLISM | |||
| row_24 | ALDH3B1 | -0.410 | Yes |
| row_25 | FAH | -0.308 | Yes |
| row_26 | ADH7 | 0.001 | Yes |
| INFLAMMATORY_RESPONSE_PATHWAY | |||
| row_10 | THBS1 | -0.678 | Yes |
| row_11 | LAMC1 | -0.564 | Yes |
| row_12 | LCK | -0.436 | Yes |
| row_13 | LAMA5 | -0.264 | Yes |
| row_14 | COL3A1 | 0.011 | Yes |
| HSA04060_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | |||
| row_176 | ACVR1B | -0.461 | Yes |
| row_177 | CCL27 | -0.457 | Yes |
| row_178 | TSLP | -0.454 | Yes |
| row_179 | TNFSF4 | -0.452 | Yes |
| row_180 | CSF1 | -0.450 | Yes |
| row_181 | TNFSF11 | -0.446 | Yes |
| row_182 | LTBR | -0.441 | Yes |
| row_183 | IL23A | -0.438 | Yes |
| row_184 | CXCR6 | -0.433 | Yes |
| row_185 | IL17RA | -0.435 | Yes |
| row_186 | TGFB2 | -0.434 | Yes |
| row_187 | EDA2R | -0.429 | Yes |
| row_188 | IL18RAP | -0.426 | Yes |
| row_189 | TGFB1 | -0.420 | Yes |
| row_190 | TNFRSF10B | -0.413 | Yes |
| row_191 | ACVR1 | -0.410 | Yes |
| row_192 | IL12RB1 | -0.413 | Yes |
| row_193 | LIF | -0.401 | Yes |
| row_194 | TNFRSF9 | -0.392 | Yes |
| row_195 | IFNGR1 | -0.377 | Yes |
| row_196 | HGF | -0.362 | Yes |
| row_197 | CCL7 | -0.346 | Yes |
| row_198 | VEGFA | -0.329 | Yes |
| row_199 | CX3CL1 | -0.312 | Yes |
| row_200 | VEGFC | -0.288 | Yes |
| row_201 | EGFR | -0.262 | Yes |
| row_202 | CXCL10 | -0.234 | Yes |
| row_203 | TGFBR2 | -0.203 | Yes |
| row_204 | CXCL12 | -0.168 | Yes |
| row_205 | IL6ST | -0.130 | Yes |
| row_206 | CCL2 | -0.091 | Yes |
| row_207 | CXCL1 | -0.047 | Yes |
| row_208 | CCL5 | 0.001 | Yes |
| UVC_LOW_C2_DN | |||
| row_12 | MYO10 | -0.534 | Yes |
| row_13 | SLIT2 | -0.362 | Yes |
| row_14 | CXCL12 | 0.004 | Yes |
| CELL_SURFACE_RECEPTOR_LINKED_SIGNAL_TRANSDUCTION | |||
| row_98 | ARHGEF2 | -0.460 | Yes |
| row_99 | ISGF3G | -0.451 | Yes |
| row_100 | IL18RAP | -0.454 | Yes |
| row_101 | TNFRSF10B | -0.445 | Yes |
| row_102 | FLNA | -0.437 | Yes |
| row_103 | ECGF1 | -0.428 | Yes |
| row_104 | IL12RB1 | -0.416 | Yes |
| row_105 | LIF | -0.397 | Yes |
| row_106 | RAMP2 | -0.380 | Yes |
| row_107 | HGF | -0.355 | Yes |
| row_108 | STC2 | -0.330 | Yes |
| row_109 | STC1 | -0.303 | Yes |
| row_110 | ANXA1 | -0.274 | Yes |
| row_111 | CD14 | -0.241 | Yes |
| row_112 | LY6E | -0.200 | Yes |
| row_113 | CXCL10 | -0.157 | Yes |
| row_114 | ADRB2 | -0.113 | Yes |
| row_115 | IL6ST | -0.057 | Yes |
| row_116 | CCL2 | 0.003 | Yes |
| HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | |||
| row_73 | RAC1 | -0.500 | Yes |
| row_74 | CCL4 | -0.495 | Yes |
| row_75 | NFKB1 | -0.497 | Yes |
| row_76 | TLR8 | -0.489 | Yes |
| row_77 | CHUK | -0.491 | Yes |
| row_78 | AKT2 | -0.487 | Yes |
| row_79 | MAP2K4 | -0.476 | Yes |
| row_80 | MAP2K3 | -0.466 | Yes |
| row_81 | MAPK3 | -0.455 | Yes |
| row_82 | IRAK1 | -0.448 | Yes |
| row_83 | TRAF3 | -0.435 | Yes |
| row_84 | JUN | -0.426 | Yes |
| row_85 | RELA | -0.416 | Yes |
| row_86 | CASP8 | -0.405 | Yes |
| row_87 | TLR2 | -0.396 | Yes |
| row_88 | SPP1 | -0.375 | Yes |
| row_89 | NFKBIA | -0.358 | Yes |
| row_90 | NFKB2 | -0.324 | Yes |
| row_91 | CD14 | -0.277 | Yes |
| row_92 | MAPK12 | -0.223 | Yes |
| row_93 | CXCL10 | -0.166 | Yes |
| row_94 | MAPK13 | -0.094 | Yes |
| row_95 | CCL5 | 0.001 | Yes |
| HSA04340_HEDGEHOG_SIGNALING_PATHWAY | |||
| row_41 | CSNK1G1 | -0.586 | Yes |
| row_42 | STK36 | -0.586 | Yes |
| row_43 | RAB23 | -0.586 | Yes |
| row_44 | GLI3 | -0.580 | Yes |
| row_45 | SUFU | -0.567 | Yes |
| row_46 | PTCH1 | -0.552 | Yes |
| row_47 | WNT3A | -0.532 | Yes |
| row_48 | BTRC | -0.530 | Yes |
| row_49 | WNT10A | -0.496 | Yes |
| row_50 | WNT10B | -0.426 | Yes |
| row_51 | WNT9A | -0.321 | Yes |
| row_52 | BMP4 | -0.164 | Yes |
| row_53 | WNT7B | 0.002 | Yes |
| GO_ROS | |||
| row_22 | LTC4S | -0.524 | Yes |
| row_23 | STK25 | -0.488 | Yes |
| row_24 | PDLIM1 | -0.416 | Yes |
| row_25 | DUSP1 | -0.279 | Yes |
| row_26 | CCL5 | 0.001 | Yes |
| LEE_E2F1_DN | |||
| row_43 | MCM10 | -0.485 | Yes |
| row_44 | PXMP2 | -0.473 | Yes |
| row_45 | ELOVL5 | -0.457 | Yes |
| row_46 | ITPR1 | -0.424 | Yes |
| row_47 | GSTO1 | -0.386 | Yes |
| row_48 | EGFR | -0.305 | Yes |
| row_49 | PPCS | -0.166 | Yes |
| row_50 | NETO2 | 0.001 | Yes |
| Specific genes enriched in wild type MEFs | |||
| PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM | |||
| row_0 | PTGIS | 0.276 | Yes |
| row_1 | CBR3 | 0.497 | Yes |
| row_2 | PTGS1 | 0.628 | Yes |
| INTRINSICPATHWAY | |||
| row_0 | PROS1 | 0.255 | Yes |
| row_1 | COL4A6 | 0.502 | Yes |
| row_2 | COL4A5 | 0.659 | Yes |
| HSA04612_ANTIGEN_PROCESSING_AND_PRESENTATION | |||
| row_0 | TAP2 | 0.277 | Yes |
| row_1 | LGMN | 0.401 | Yes |
| row_2 | PSME1 | 0.432 | Yes |
| row_3 | TAP1 | 0.448 | Yes |
| row_4 | CIITA | 0.480 | Yes |
| row_5 | HSP90AA1 | 0.514 | Yes |
| LAL_KO_3MO_UP | |||
| row_0 | PLA2G7 | 0.221 | Yes |
| row_1 | GPNMB | 0.426 | Yes |
| row_2 | TREM2 | 0.487 | Yes |
| row_3 | FKBP5 | 0.478 | Yes |
| row_4 | SLC40A1 | 0.507 | Yes |
| GH_AUTOCRINE_UP | |||
| row_0 | ID3 | 0.053 | Yes |
| row_1 | SCAMP5 | 0.104 | Yes |
| row_2 | ALCAM | 0.154 | Yes |
| row_3 | IGFBP7 | 0.193 | Yes |
| row_4 | COL4A6 | 0.232 | Yes |
| row_5 | TLE2 | 0.267 | Yes |
| row_6 | BLVRB | 0.295 | Yes |
| row_7 | GRIA1 | 0.324 | Yes |
| row_8 | SFXN5 | 0.344 | Yes |
| row_9 | ID1 | 0.368 | Yes |
| row_10 | PPA2 | 0.386 | Yes |
| row_11 | VTI1A | 0.391 | Yes |
| row_12 | UQCR | 0.394 | Yes |
| row_13 | ADK | 0.408 | Yes |
| row_14 | MOBKL2B | 0.420 | Yes |
| row_15 | SPATA7 | 0.429 | Yes |
| row_16 | MRPL28 | 0.431 | Yes |
| row_17 | SH3KBP1 | 0.439 | Yes |
| row_18 | CFL2 | 0.442 | Yes |
| row_19 | BSG | 0.444 | Yes |
| row_20 | MOGAT2 | 0.451 | Yes |
| row_21 | SSR4 | 0.459 | Yes |
| row_22 | SAR1B | 0.465 | Yes |
| row_23 | PIR | 0.467 | Yes |
| row_24 | AXL | 0.469 | Yes |
| row_25 | GMPR | 0.475 | Yes |
| row_26 | PSMB2 | 0.481 | Yes |
| row_27 | SLC43A1 | 0.485 | Yes |
| row_28 | GPR12 | 0.482 | Yes |
| row_29 | G3BP | 0.488 | Yes |
| HSA02010_ABC_TRANSPORTERS_GENERAL | |||
| row_0 | TAP2 | 0.192 | Yes |
| row_1 | ABCD4 | 0.294 | Yes |
| row_2 | ABCA3 | 0.353 | Yes |
| row_3 | ABCC10 | 0.418 | Yes |
| row_4 | ABCC5 | 0.465 | Yes |
| row_5 | ABCC3 | 0.503 | Yes |
| row_6 | ABCA7 | 0.534 | Yes |
| row_7 | TAP1 | 0.540 | Yes |
| IL2RBPATHWAY | |||
| row_0 | JAK3 | 0.217 | Yes |
| row_1 | SOCS3 | 0.274 | Yes |
| row_2 | MAPK1 | 0.353 | Yes |
| row_3 | SOCS1 | 0.429 | Yes |
| row_4 | IRS1 | 0.499 | Yes |
| row_5 | CRKL | 0.545 | Yes |
| SMITH_HCV_INDUCED_HCC_UP | |||
| row_0 | GSTA4 | 0.309 | Yes |
| row_1 | SDHC | 0.378 | Yes |
| row_2 | PMVK | 0.386 | Yes |
| row_3 | PDCD5 | 0.416 | Yes |
| row_4 | PIR | 0.450 | Yes |
| row_5 | IMPA2 | 0.469 | Yes |
| row_6 | COPS5 | 0.485 | Yes |
| row_7 | ANXA7 | 0.510 | Yes |
| row_8 | NOLA2 | 0.523 | Yes |
| HOX_GENES | |||
| row_0 | HOXD4 | 0.092 | Yes |
| row_1 | HOXB5 | 0.176 | Yes |
| row_2 | HOXA5 | 0.251 | Yes |
| row_3 | HOXA2 | 0.319 | Yes |
| row_4 | MEIS1 | 0.376 | Yes |
| row_5 | PRRX1 | 0.414 | Yes |
| row_6 | HOXA7 | 0.461 | Yes |
| row_7 | HOXD3 | 0.500 | Yes |
| NI2_LUNG_DN | |||
| row_0 | TRAP1 | 0.257 | Yes |
| row_1 | CEBPD | 0.470 | Yes |
| row_2 | ABCC3 | 0.584 | Yes |
| row_3 | LGTN | 0.639 | Yes |
| row_4 | HSP90AA1 | 0.702 | Yes |
| MAGRANGEAS_MULTIPLE_MYELOMA_IGL_VS_IGK_DN | |||
| row_0 | GSTM5 | 0.178 | Yes |
| row_1 | TJP2 | 0.328 | Yes |
| row_2 | SMARCA1 | 0.407 | Yes |
| row_3 | CSNK2A2 | 0.466 | Yes |
| row_4 | UBE4A | 0.503 | Yes |
| HSA04630_JAK_STAT_SIGNALING_PATHWAY | |||
| row_0 | JAK3 | 0.054 | Yes |
| row_1 | SOCS2 | 0.111 | Yes |
| row_2 | IL11 | 0.166 | Yes |
| row_3 | OSMR | 0.214 | Yes |
| row_4 | STAT3 | 0.253 | Yes |
| row_5 | IFNGR2 | 0.270 | Yes |
| row_6 | SOCS3 | 0.281 | Yes |
| row_7 | CCND2 | 0.300 | Yes |
| row_8 | SOCS1 | 0.319 | Yes |
| row_9 | CTF1 | 0.338 | Yes |
| row_10 | SOCS5 | 0.358 | Yes |
| row_11 | GHR | 0.369 | Yes |
| row_12 | PIK3R2 | 0.382 | Yes |
| row_13 | CISH | 0.392 | Yes |
| row_14 | SPRY4 | 0.406 | Yes |
| row_15 | IL15 | 0.398 | Yes |
| row_16 | SPRY3 | 0.408 | Yes |
| row_17 | STAT1 | 0.418 | Yes |
| row_18 | CCND1 | 0.426 | Yes |
| row_19 | PIAS4 | 0.429 | Yes |
| row_20 | AKT3 | 0.435 | Yes |
| row_21 | CREBBP | 0.441 | Yes |
| row_22 | PIK3R5 | 0.437 | Yes |
| row_23 | GRB2 | 0.442 | Yes |
| row_24 | LEPR | 0.449 | Yes |
| row_25 | IFNAR2 | 0.440 | Yes |
| row_26 | PIAS3 | 0.438 | Yes |
| row_27 | JAK2 | 0.443 | Yes |
| row_28 | EPO | 0.448 | Yes |
| row_29 | CBLB | 0.447 | Yes |
| row_30 | TYK2 | 0.451 | Yes |
| GLUTATHIONE_METABOLISM | |||
| row_0 | GSTA4 | 0.165 | Yes |
| row_1 | GSTM2 | 0.297 | Yes |
| row_2 | IDH1 | 0.384 | Yes |
| row_3 | GSTM5 | 0.469 | Yes |
| row_4 | GSTM1 | 0.555 | Yes |
| row_5 | GSTZ1 | 0.625 | Yes |
| row_6 | GSTO2 | 0.699 | Yes |
| HSA03022_BASAL_TRANSCRIPTION_FACTORS | |||
| row_0 | GTF2H4 | 0.132 | Yes |
| row_1 | GTF2F2 | 0.182 | Yes |
| row_2 | TAF13 | 0.264 | Yes |
| row_3 | TBPL2 | 0.333 | Yes |
| row_4 | GTF2E1 | 0.375 | Yes |
| row_5 | TAF7L | 0.420 | Yes |
| row_6 | TAF9B | 0.466 | Yes |
| row_7 | GTF2I | 0.511 | Yes |
| row_8 | GTF2H3 | 0.528 | Yes |
| row_9 | TAF6L | 0.562 | Yes |
| row_10 | GTF2A1 | 0.583 | Yes |
| SPPAPATHWAY | |||
| row_0 | PTGS1 | 0.273 | Yes |
| row_1 | GNB1 | 0.391 | Yes |
| row_2 | MAPK1 | 0.500 | Yes |
| TNFALPHA_TGZ_ADIP_DN | |||
| row_0 | IDH1 | 0.218 | Yes |
| row_1 | ALAD | 0.362 | Yes |
| row_2 | RGS2 | 0.495 | Yes |
| row_3 | IDH3G | 0.591 | Yes |
| row_4 | CDKN2C | 0.662 | Yes |
| ADIP_HUMAN_UP | |||
| row_0 | ADORA2B | 0.136 | Yes |
| row_1 | ALDH6A1 | 0.247 | Yes |
| row_2 | LPL | 0.345 | Yes |
| row_3 | RXRA | 0.383 | Yes |
| row_4 | ACSL1 | 0.381 | Yes |
| row_5 | CRYAB | 0.410 | Yes |
| row_6 | PFKFB3 | 0.437 | Yes |
| row_7 | LYPLA1 | 0.465 | Yes |
| row_8 | RXRB | 0.469 | Yes |
| row_9 | KCNH2 | 0.483 | Yes |
| row_10 | LBP | 0.476 | Yes |
| row_11 | CTSG | 0.464 | Yes |
| row_12 | GPD1 | 0.475 | Yes |
| row_13 | DGAT1 | 0.482 | Yes |
| row_14 | PLCD1 | 0.490 | Yes |
| row_15 | ATP8A2 | 0.496 | Yes |
| row_16 | ABCE1 | 0.499 | Yes |
| row_17 | FABP5 | 0.493 | Yes |
| row_18 | SMARCB1 | 0.499 | Yes |
| ERKPATHWAY | |||
| row_0 | STAT3 | 0.180 | Yes |
| row_1 | PDGFRA | 0.290 | Yes |
| row_2 | GNB1 | 0.401 | Yes |
| BRCA1_SW480_DN | |||
| row_0 | GRB10 | 0.390 | Yes |
| row_1 | COL16A1 | 0.462 | Yes |
| row_2 | RXRB | 0.475 | Yes |
| row_3 | BAX | 0.486 | Yes |
| row_4 | SEMA3B | 0.515 | Yes |
| row_5 | GRB2 | 0.537 | Yes |
| row_6 | PIN1 | 0.555 | Yes |
| NF90_DN | |||
| row_0 | SLC1A3 | 0.276 | Yes |
| row_1 | CXCR7 | 0.355 | Yes |
| row_2 | IRX5 | 0.449 | Yes |
| row_3 | ASNS | 0.485 | Yes |
| row_4 | RAD52 | 0.514 | Yes |
| row_5 | CUGBP2 | 0.545 | Yes |
| row_6 | AXL | 0.567 | Yes |
| row_7 | CREBBP | 0.589 | Yes |
| row_8 | NMT1 | 0.606 | Yes |
| row_9 | GAL | 0.606 | Yes |
| row_10 | POLD2 | 0.612 | Yes |
| HSA04742_TASTE_TRANSDUCTION | |||
| row_0 | TAS1R2 | 0.322 | Yes |
| row_1 | GNB1 | 0.410 | Yes |
| row_2 | PRKX | 0.461 | Yes |
| row_3 | TAS1R3 | 0.452 | Yes |
| row_4 | PRKACA | 0.485 | Yes |
| ET743PT650_COLONCA_DN | |||
| row_0 | ALCAM | 0.180 | Yes |
| row_1 | TIAM1 | 0.255 | Yes |
| row_2 | ID1 | 0.339 | Yes |
| row_3 | COMMD1 | 0.394 | Yes |
| row_4 | ATBF1 | 0.438 | Yes |
| HSA00590_ARACHIDONIC_ACID_METABOLISM | |||
| row_0 | PTGIS | 0.192 | Yes |
| row_1 | CBR3 | 0.345 | Yes |
| row_2 | PTGS1 | 0.434 | Yes |
| STAEGE_EFTS_UP | |||
| row_0 | CYP26B1 | 0.191 | Yes |
| row_1 | CCK | 0.337 | Yes |
| row_2 | KCNAB3 | 0.410 | Yes |
| row_3 | EGR2 | 0.436 | Yes |
| row_4 | TMEM29 | 0.462 | Yes |
| row_5 | CCND1 | 0.484 | Yes |
| row_6 | ZDHHC21 | 0.492 | Yes |
| row_7 | CLEC11A | 0.499 | Yes |
The criteria for the GSEA analysis was P < 0.05 and false discovery rate (FDR) <25%.