Fig. 3.

Comparative efficacies of vancomycin and daptomycin ALT (both at 5 mg/ml) for 18 h daily for three consecutive days against two different strains of MRSE, biofilm-forming strains ATCC 700565 and ATCC 49461. (A) Bacterial titers in central venous catheter blood draws before (0 ALT), during (1 ALT and 2 ALT), and after (3 ALT) ALT, including terminal central venous catheter blood draws, catheter harvesting, and cardiac blood draws 7 days following the cessation of ALT (3 ALT + 7 days). (B) Bacterial titers measured at metastatic sites of infection, including the vena cava (surrounding the central venous catheter), heart, lung, kidneys, and spleen.