. 2011 Sep;55(9):4012–4018. doi: 10.1128/AAC.00223-11

Table 3.

In vitro susceptibilities to three distinct CAPs, cell membrane fluidity, and cell wall thickness of 10 study strain pairs^a

Strain	% survival (mean ± SD) after 2 h of exposure to:						Cell membrane fluidity (PI value)	Cell wall thickness (nm)
	tPMPs		hNP-1		PMB
	0.5 μg/ml	0.25 μg/ml	10 μg/ml	5 μg/ml	40 μg/ml	20 μg/ml
CB1483	18 ± 12	32 ± 18	45 ± 11	59 ± 11	7 ± 8	31 ± 18	0.333 ± 0.012	35.9 ± 3.8
CB185	67 ± 22^*	95 ± 10^*	56 ± 8	69 ± 14	9 ± 11	38 ± 16	0.331 ± 0.004	38.8 ± 3.4^**
CB5079	3 ± 4	22 ± 8	3 ± 6	21 ± 7	0 ± 0	40 ± 18	0.453 ± 0.042	30.7 ± 3.2
CB5080	48 ± 7^*	74 ± 11^*	40 ± 5^*	60 ± 13^*	37 ± 7^*	65 ± 19	0.369 ± 0.047	39.3 ± 4.2^***
CB5083	14 ± 7	32 ± 15	0 ± 0	0 ± 0	0 ± 0	33 ± 18	0.394 ± 0.064	30.6 ± 3.1
CB5082	78 ± 10^*	83 ± 12^*	33 ± 13^*	48 ± 8^*	52 ± 7^*	77 ± 14^*	0.325 ± 0.046	37.0 ± 4.1^***
CB5088	3 ± 2	17 ± 8	9 ± 9	20 ± 13	5 ± 8	52 ± 10	0.388 ± 0.033	33.7 ± 3.3
CB5089	41 ± 3^*	76 ± 17^*	19 ± 9	40 ± 9	26 ± 7^*	59 ± 3	0.343 ± 0.008	34.6 ± 2.6^*
CB1631	22 ± 12	31 ± 24	15 ± 14	30 ± 24	6 ± 7	46 ± 25	0.375 ± 0.021	39.7 ± 3.5
CB1634	87 ± 8^*	100 ± 12^*	72 ± 16^*	79 ± 10^*	12 ± 9	56 ± 28	0.280 ± 0.045^*	39.8 ± 3.5
CB1663	0 ± 0	0 ± 0	0 ± 0	0 ± 0	0 ± 0	20 ± 5	0.422 ± 0.081	29.4 ± 3.0
CB1664	84 ± 36^*	82 ± 39^*	67 ± 17^*	64 ± 14^*	57 ± 21^*	69 ± 5^*	0.334 ± 0.075	44.7 ± 5.3^*
CB5057	80 ± 10	80 ± 6	24 ± 6	34 ± 5	40 ± 24	85 ± 1	0.321 ± 0.022	34.2 ± 4.4
CB5059	94 ± 13	95 ± 19	70 ± 21^*	76 ± 20^*	69 ± 20	83 ± 13	0.265 ± 0.054	36.0 ± 3.6^*
CB5062	69 ± 27	74 ± 35	23 ± 9	44 ± 8	0 ± 0	7 ± 12	0.332 ± 0.098	32.3 ± 3.0
CB5063	85 ± 2	96 ± 7	64 ± 33	69 ± 28	20 ± 21	56 ± 23^*	0.331 ± 0.014	36.2 ± 4.0^***
CB5015	80 ± 36	82 ± 28	65 ± 7	66 ± 3	44 ± 12	58 ± 1	0.375 ± 0.051	41.4 ± 6.7
CB5016	85 ± 32	92 ± 19	87 ± 8^*	82 ± 3^*	50 ± 10	48 ± 8	0.342 ± 0.035	43.1 ± 6.1^b
CB5021	24 ± 11	57 ± 14	16 ± 12	28 ± 24	22 ± 13	66 ± 13	0.295 ± 0.020	30.4 ± 3.8
CB5020	101 ± 16^*	111 ± 5^*	83 ± 5^*	73 ± 6^*	82 ± 30^*	95 ± 41	0.083 ± 0.04^*	47.7 ± 7.5^***

Pairs of isolates are represented by alternative shading and no shading, with the first strain in each pair being the DAP^s parental strain and the second one in each pair being the DAP^r strain. *, P < 0.05 versus parental strain; **, P = 0.05 versus parental strain; ***, P < 0.0001 versus parental strain.

P = 0.057 versus parental strain value.