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. 2011 Sep;55(9):4012–4018. doi: 10.1128/AAC.00223-11

Table 5.

Comparative analysis of CAP susceptibility, cell membrane fluidity, and cell wall thickness of the DAPs parental strains and the 7 DAPr strains with mutations in mprF (with or without yycG mutations)a

Parameter DAPs strains (n = 10) DAPr strains (n = 7) P value
% survival after 2 h of exposure to CAP (concnb)
    tPMP (0.50) 31 ± 32 71 ± 20 0.0112
    tPMP (0.25) 43 ± 29 86 ± 10 0.016
    hNP-1 (10) 20 ± 21 51 ± 21 0.0085
    hNP-1 (5) 30 ± 22 62 ± 14 0.0041
    PMB (40) 12 ± 17 37 ± 23 0.0207
    PMB (20) 44 ± 23 64 ± 15 0.0599
Cell membrane fluidity (PI value) 0.369 ± 0.05 0.321 ± 0.04 0.0441
Cell wall thickness (nm) 33.84 ± 4.1 38.60 ± 3.3 0.0218
a

Values are means ± SDs.

b

Concentrations are in micrograms per milliliter.

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