Table 4.
Inventory of antibiotic resistance genes identified in whole K. pneumoniae genomes
| Groupa | No. of genesb |
||||||
|---|---|---|---|---|---|---|---|
| 1162281 | JH1 | MGH | NTUH | Rh | 342 | Other Klebsiella spp.c | |
| Aminoglycoside acetyltransferase | 0 | 0 | 4 | 0 | 0 | 0 | 130 |
| Aminoglycoside phosphotransferase | 1 | 0 | 1 | 0 | 0 | 0 | 15 |
| Beta-lactamase | 3 | 1 | 4 | 1 | 1 | 2 | 915 |
| Chloramphenicol acetyltransferase | 1 | 0 | 1 | 0 | 0 | 0 | 33 |
| Drug-insensitive DHFR | 1 | 0 | 0 | 0 | 0 | 0 | 70 |
| Specific demethylase | 1 | 1 | 1 | 1 | 1 | 1 | 3 |
| Efflux pump | 12 | 11 | 13 | 11 | 11 | 11 | 44 |
| Pentapeptide repeat | 1 | 0 | 0 | 0 | 0 | 0 | 49 |
| Sulfonamide-resistant dihydropteroate synthase | 1 | 0 | 1 | 0 | 0 | 0 | 60 |
| Ribosomal protection protein | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Undecaprenyl pyrophosphate phosphatase | 1 | 1 | 1 | 1 | 1 | 1 | 2 |
| Unclassified | 2 | 2 | 2 | 2 | 2 | 2 | 4 |
| Total | 24 | 16 | 28 | 16 | 16 | 17 | 1,326 |
a
Antibiotic resistance gene categories were adapted from the ARDB and identified by TBLASTN searches.
b
Species name abbreviations are the same as those in Table 2.
c
Other Klebsiella sp. hits from the GenBank database.