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. 2011 Sep;55(9):4211–4217. doi: 10.1128/AAC.00561-11

Table 2.

Resistance phenotype characterization and FIC/FBC index values of NB-003–BPO against P. acnes isolates

Strain no. Resistance phenotypea Average synergy indicesb
FIC FBC
PAC-001 Erys Clis Tets (ATCC6919) 0.4 0.2
PAC-003 Erys Clis Tets (ATCC11828) 0.4 0.4
PAC-004 Erys Clis Tets 0.6 0.5
PAC-005 Erys Clir Tets (unknown) 0.4 0.7
PAC-006 Eryr Clir Tetr (G2057A + G1058C) 0.5 0.3
PAC-007 Eryr Clir Tetr (A2058G + G1058C) 0.4 0.3
PAC-008 Eryr Clir Tetr (A2058G + G1058C) 0.4 0.4
PAC-009 Eryr Clir Tets (A2059G) 0.5 0.6
PAC-010 Eryr Clir Tetr (A2059G + G1058C) 0.5 0.4
PAC-011 Eryr Clir Tets (ermX) 0.4 0.4
PAC-002 Erys Clis Tets (ATCC11827) NA NA
PAC-012 Erys Clis Tetr (G1058C) NA NA
PAC-013 Eryr Clir Tetr (unknown) NA NA
PAC-014 Eryr Clir Tetr (ermX) NA NA
PAC-015 Eryr Clir Tets (G2057A) NA NA
PAC-016 Eryr Clir Tets (A2058G) NA NA
a

Erys/r, erythromycin susceptible/resistant; Clis/r, clindamycin susceptible/resistant; Tets/r, tetracycline susceptible/resistant. The resistance breakpoints are erythromycin, ≥0.5 μg/ml; clindamycin, ≥0.25 μg/ml; tetracycline, ≥2 μg/ml. Unknown, the genetic basis of antibiotic resistance is unknown.

b

NA, not tested in synergy study.