Table 2.
Strain no. | Resistance phenotypea | Average synergy indicesb |
|
---|---|---|---|
FIC | FBC | ||
PAC-001 | Erys Clis Tets (ATCC6919) | 0.4 | 0.2 |
PAC-003 | Erys Clis Tets (ATCC11828) | 0.4 | 0.4 |
PAC-004 | Erys Clis Tets | 0.6 | 0.5 |
PAC-005 | Erys Clir Tets (unknown) | 0.4 | 0.7 |
PAC-006 | Eryr Clir Tetr (G2057A + G1058C) | 0.5 | 0.3 |
PAC-007 | Eryr Clir Tetr (A2058G + G1058C) | 0.4 | 0.3 |
PAC-008 | Eryr Clir Tetr (A2058G + G1058C) | 0.4 | 0.4 |
PAC-009 | Eryr Clir Tets (A2059G) | 0.5 | 0.6 |
PAC-010 | Eryr Clir Tetr (A2059G + G1058C) | 0.5 | 0.4 |
PAC-011 | Eryr Clir Tets (ermX) | 0.4 | 0.4 |
PAC-002 | Erys Clis Tets (ATCC11827) | NA | NA |
PAC-012 | Erys Clis Tetr (G1058C) | NA | NA |
PAC-013 | Eryr Clir Tetr (unknown) | NA | NA |
PAC-014 | Eryr Clir Tetr (ermX) | NA | NA |
PAC-015 | Eryr Clir Tets (G2057A) | NA | NA |
PAC-016 | Eryr Clir Tets (A2058G) | NA | NA |
Erys/r, erythromycin susceptible/resistant; Clis/r, clindamycin susceptible/resistant; Tets/r, tetracycline susceptible/resistant. The resistance breakpoints are erythromycin, ≥0.5 μg/ml; clindamycin, ≥0.25 μg/ml; tetracycline, ≥2 μg/ml. Unknown, the genetic basis of antibiotic resistance is unknown.
NA, not tested in synergy study.