Table 4.
Frequency of spontaneous mutations for 16 strains of P. acnes
| Strain no. | Spontaneous mutation frequencya |
|||
|---|---|---|---|---|
| MIC | 2× MIC | 4× MIC | 8× MIC | |
| PAC-001 | 7.7 × 10−11 | <7.7 × 10−11 | <7.7 × 10−11 | <7.7 × 10−11 |
| PAC-002 | 3.4 × 10−10 | <6.9 × 10−11 | <6.9 × 10−11 | <6.9 × 10−11 |
| PAC-003 | <5.6 × 10−11 | <5.6 × 10−11 | <5.6 × 10−11 | <5.6 × 10−11 |
| PAC-004 | 2.0 × 10−10 | <4.0 × 10−11 | <4.0 × 10−11 | <4.0 × 10−11 |
| PAC-005 | 9.6 × 10−10 | <1.9 × 10−10 | <1.9 × 10−10 | <1.9 × 10−10 |
| PAC-006 | <9.1 × 10−11 | <9.1 × 10−11 | <9.1 × 10−11 | <9.1 × 10−11 |
| PAC-007 | <3.8 × 10−11 | <3.8 × 10−11 | <3.8 × 10−11 | <3.8 × 10−11 |
| PAC-008 | <2.7 × 10−11 | <2.7 × 10−11 | 5.5 × 10−11 | <2.7 × 10−11 |
| PAC-009 | 4.4 × 10−08 | <2.2 × 10−10 | <2.2 × 10−10 | <2.2 × 10−10 |
| PAC-010 | <1.3 × 10−10 | <1.3 × 10−10 | <1.3 × 10−10 | <1.3 × 10−10 |
| PAC-011 | <2.5 × 10−11 | 2.5 × 10−11 | <2.5 × 10−11 | <2.5 × 10−11 |
| PAC-012 | <2.7 × 10−10 | <2.7 × 10−10 | <2.7 × 10−10 | <2.7 × 10−10 |
| PAC-013 | <3.4 × 10−11 | <3.4 × 10−11 | <3.4 × 10−11 | <3.4 × 10−11 |
| PAC-014 | <1.0 × 10−07 | <1.0 × 10−07 | <1.0 × 10−07 | <1.0 × 10−07 |
| PAC-015 | <3.8 × 10−10 | <3.8 × 10−10 | <3.8 × 10−10 | <3.8 × 10−10 |
| PAC-016 | <1.0 × 10−07 | <1.0 × 10−07 | <1.0 × 10−07 | <1.0 × 10−07 |
a
Concentration shown as multiples of the MIC of NB-003 against the parent strain.