Table 4.
Changes in the wall proteome of planktonic cultures of C. albicans induced by Congo red as indicated by the total number of identifications of tryptic peptides from secretory proteins
| Protein | Peptide counta |
CR/control ratiob | |
|---|---|---|---|
| CR (7 runs) | Control (8 runs) | ||
| Pga31 | 14 | ND | |
| Sap9 | 6 | ND | |
| Pir1 | 6 | 1 | 6.9 |
| Phr2 | 12 | 3 | 4.6 |
| Sod5 | 18 | 9 | 2.3 |
| Utr2 | 22 | 11 | 2.3 |
| Phr1 | 33 | 17 | 2.2 |
| Rhd3 | 21 | 11 | 2.2 |
| Rbt5 | 7 | 4 | 2.0 |
| Crh11 | 51 | 33 | 1.8 |
| Ecm33 | 35 | 23 | 1.7 |
| Mp65 | 19 | 14 | 1.6 |
| Ywp1 | 7 | 8 | 1.0 |
| Cht2 | 20 | 25 | 0.9 |
| Pga4 | 9 | 12 | 0.9 |
| Sod4 | 12 | 22 | 0.6 |
| Ssr1 | 7 | 15 | 0.5 |
| Als3 | ND | 8 | |
a
Number of tryptic peptides. Four biological replicates were analyzed for both conditions. Each biological replicate was analyzed twice (giving a maximum of 8 runs), except for Congo red, where biological replicate 1 was analyzed only once (7 runs). Congo red (CR) was used at 2 mg/liter. For sequence information of the peptides identified in control and in FCZ-treated cultures, see Tables S5 and S6, respectively, in the supplemental material. ND, not detected.
b
The ratios are normalized for the number of runs.