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. 2011 Sep;79(9):3607–3618. doi: 10.1128/IAI.05043-11

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Fig. 1. — Kaplan-Meier survival plots for wild-type (WT), Rab27a^ash^/^ash (ashen), and Munc13-4 ^jinx^/^jinx (jinx) mice. Mice were challenged with a single intraperitoneal injection of LPS (7 mg/kg [A] or 12 mg/kg [B]). Survival curves were generated from two independent experiments with a total of 12 Rab27a^ash^/^ash, 12 Munc13-4^jinx^/^jinx, and 18 wild-type mice. The difference in survival between the wild-type and Rab27a^ash^/^ash mice was significant (**, P = 0.0012) by the log-rank test. Although less significant, the difference in survival between wild-type and Munc13-4^jinx^/^jinx mice was also evident (*, P = 0.05).