Fig. 6.

Cytokine secretion profiles of splenocytes of BALB/c mice immunized with P. vivax recombinant immunogens. The cytokines IFN-γ (A), IL-4 (B), and IL-10 (C) were analyzed by ELISA in cell culture supernatants after in vitro restimulation with recombinant PvAMA-1 of splenocytes of the different groups of mice (as indicated) immunized 14 weeks before. Plots are representative of two different experiments that included a total of six animals per group, analyzed in pools of three. Numbers represent means ± standard errors of the means (SEM).