Table 2.
Characteristics of functional processes for the degradation of HMW PAHs
Parameter | Characteristics of: |
||
---|---|---|---|
RCP | SCP | CAP | |
Input | (HMW) PAHs | Ring cleavage compounds | Protocatechuate |
Output | Ring cleavage compounds | Pyruvate | Acetyl-CoA/succinyl-CoA |
Metabolites acceptable to RCP | |||
Metabolite centric | Relatively highly branched pathways | Linear or less branched pathways | Partial RCP and SCP |
High-degree metabolites | Low-degree metabolites | Linear pathway | |
Gradual increase in MW | Gradual decrease in MW | ||
Enzyme centric | O2dependent | Productive | Productive |
Non-productive metabolites | Constitutively/loosely regulated | Constitutive expression | |
Tightly regulated | Generally broad substrate specificities | Entering TCA cycle | |
Diverse substrate specificity | Preparative for RCP or CAP | Belong to EC 1-5 | |
Pathway determining | Belong to EC 1-5 | ||
Preparative for SCP | |||
Mostly belong to EC 1 |