. 2011 Sep;49(9):3380–3382. doi: 10.1128/JCM.00908-11

Table 1.

Viral and host factors associated with disagreement in HIV-1 tropism prediction using geno2pheno and PSSM

Characteristic	Value for:
	Geno2pheno_{FPR = 10%} vs. PSSM_X4/R5				Geno2pheno_{FPR = 10%} vs. PSSM_SI/NSI
	Concordant	Discordant	P value^a		Concordant	Discordant	P value^a
	Concordant	Discordant	Univariate	Multivariate	Concordant	Discordant	Univariate	Multivariate
CD4 count [IQR] (no. of cells/mm³)	315 [197–504]	304 [161–475]	0.496	0.647	316 [189–511]	304 [207–451]	0.486	0.704
Plasma HIV-RNA [IQR] (no. of log copies/ml)	4.20 [3.21–4.91]	4.28 [3.41–4.94]	0.612	0.580	4.24 [3.22–4.92]	4.23 [3.40–4.81]	0.825	0.786
Viral subtype (% non-B)	11.3	19.6	0.018	0.867	11.6	17.7	0.099	0.696
ARV exposure (% naïve)	47.2	56.3	0.132	0.150	52.2	46.8	0.395	0.333
Amino acid length (% without 35 aa)	17.5	38.3	<0.001	<0.001	17.3	41.7	<0.001	<0.001
Nucleotide mixture (% presence)	69.4	69.8	0.652	0.988	70.0	67.7	0.637	0.564
Glycosylation site (% absence)	2.9	4.7	0.364	0.707	3.0	4.2	0.528	0.724

Significant P values are highlighted in boldface type.