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Principle of SNP analysis by using two independent SNP genotyping technologies: the SNaPshot technology (Applied Biosystems) and the iPLEX technology (Sequenom). These genotyping methods comprise three main steps, namely, PCR amplification of the DNA region containing the polymorphic site (step 1), an allelic discrimination reaction consisting of an SBE reaction (step 2), and detection of allele-specific products (step 3).
