Table 1.
Performance comparison of CAM, CAP/CTM, and the prototype CAP/CTM v2/MMx1 and v2/MMx2 assays for the determination of HCV RNA concentrations in patients infected with genotypes 1 to 6
| GT | No. of samples | CAM (reference assay) |
CAP/CTM |
CAP/CTM v2/MMx1 |
CAP/CTM v2/MMx2 |
||||
|---|---|---|---|---|---|---|---|---|---|
| Mean IU/ml | Mean log10IU/ml | Mean log10 | Difference to CAM | Mean log10 | Difference to CAM | Mean log10 | Difference to CAM | ||
| GT1 | 108 | 3.9 × 104 | 4.59 | 4.60 | 0.01 | 4.73 | 0.14 | 4.54 | -0.05 |
| GT2 | 8 | 8.1 × 104 | 4.91 | 4.49 | -0.42 | 4.89 | -0.02 | 4.96 | 0.05 |
| GT3 | 24 | 8.4 × 104 | 4.93 | 4.46 | -0.47 | 5.18 | 0.25 | 4.81 | -0.12 |
| GT4 | 87 | 3.0 × 104 | 4.48 | 3.85 | -0.63 | 4.59 | 0.11 | 4.38 | -0.10 |
| GT5 | 3 | 1.9 × 104 | 5.29 | 4.62 | -0.67 | 5.28 | -0.01 | 4.85 | -0.44 |
| GT6 | 2 | 8.6 × 104 | 4.94 | 4.51 | -0.43 | 4.87 | -0.07 | 4.65 | -0.29 |