Fig. 2.

Oncoselectivity and IFN pretreatment effects. Three primary mesoderm-derived cell cultures and three sarcomas were infected with VSV-rp30a at MOI 0.2 PFU/cell. Cells were either infected without (A) or with (B) IFN pretreatment (100 U/ml for 6 h). The percentage of cells expressing GFP was assessed in triplicate wells for each condition, and bars represent standard errors. hFib, normal human fibroblasts; hDecid, normal human decidua; mBVE, mouse brain vascular endothelium; MPNS, malignant peripheral nerve sheath tumor; ESFT, Ewing's sarcoma family tumor; Osteo., osteosarcoma 132.98.2.