Table 3.

Properties of PA-binding partners as determined by DAVID

GO term	DAVID functional annotationd	Group of 166 proteinsa		Combined group of 306 proteinsb
		No. of molecules	P valuec	No. of molecules	P valuec
Biological process	Intracellular transport	32	1.40E−09	46	3.10E−10
	Intracellular protein transport	20	2.20E−06	24	6.80E−05
	COPI coating of Golgi vesicle	6	4.00E−06	7	2.10E−06
	Nucleocytoplasmic transport	12	5.60E−05	15	1.10E−04
Molecular function	Nucleotide binding	54	2.10E−07	108	1.20E−19
	Protein transporter activity	9	1.20E−04	11	1.40E−04
	ATPase activity	13	5.60E−03	32	1.20E−11
Cellular component	Organelle envelope	35	3.60E−13	60	5.40E−22
	Pore complex	13	2.50E−08	15	1.70E−07
	COPI vesicle coat	6	1.70E−06	7	7.00E−07
	Mitochondrion	33	2.30E−06	66	1.30E−14
	Endoplasmic reticulum	27	1.30E−04	42	5.20E−05

^aRNA-independent factors.

^bUnion of RNA-dependent and -independent factors (166 + 140 proteins).

^cP values were determined by a Benjamini-Hochberg multiple testing correction.

^dThe mitochondrion category is highlighted as being of particular importance (see text).