Table 2.
VRC01-resistant virus reversion mutant mutagenesis and binding/neutralization profilec
aB-EC50 (μg/ml), half-maximal effective concentration of ELISA binding assay.
bN-IC50 (μg/ml), 50% inhibitory concentration of neutralization assay.
cThree VRC01-sensitive virus gp120 sequences are listed at top as references. VRC01-resistant virus gp120 variations from the reference sequences are listed in bold red type. The mutated residues are marked in bold black type and underlined.