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. 2011 Sep;85(17):8929–8939. doi: 10.1128/JVI.00336-11

Fig. 1.

Fig. 1.

Diagram of the partial sequences of the construct aLTIII. The 1,918-bp EBV sequence was placed under the control of the CMV promoter (open box) and BGH polyadenylation signal, and the nucleotides are numbered between positions −121 and 1797. A small arrowhead shows the start site and orientation of transcription initiated by the CMV promoter. The CMV promoter initiated RNA transcript starts at nt −261 and has 139-nt non-EBV leader sequences. The dotted lines represent sequences not shown. The sequences of pre-miR-BHRF1-1, pre-miR-BHRF1-2, and pre-miR-BHRF1-3 are underlined and indicated as miR1, miR2, and miR3. The TATA box (TATTA) and transcription start site (nucleotide position 1) of the EBV lytic replication-activated BHRF1 promoter and polyadenylation signal (AATAAA) are in boldface. The splice donor, acceptor, and 439-nt intron in brackets are indicated. The partial BHRF1 amino acid sequences are shown under corresponding codons.