Fig. 1.

HIV-1 capture by MAbs b12 and b6 was enhanced in the presence of GRFT. HIV-1 env-pseudotyped viruses from subtype B (QH0692.42 and PVO.4) and subtype C (COT6.15, COT9.6, Du151.2, and CAP239.G3J) were incubated with three different concentrations of GRFT before being added to plates coated with either b12 (A) or b6 (B). The amount of captured virus was assessed by p24 ELISA. Each MAb was also competed against itself as a positive control. The controls (black bars) show the amounts of virus captured on b12- or b6-coated plates in the absence of GRFT. The bars represent the means and standard deviations (SD) of three different experiments.