Figure 3.

Dose-dependent effects of several pure cannabinoids on lysophosphatidylcholine (LPC, 3 µM)-induced, TRP channel of vanilloid type-2 (TRPV2)-mediated elevation of intracellular calcium in HEK-293 cells stably over-expressing the rat recombinant TRPV2 channel. Compounds were given to cells 5 min prior to LPC. Data are means of at least n = 3 separate experiments. SEM are not shown for the sake of clarity and were never higher than 10% of the means. CBC, cannabichromene; CBD, cannabidiol; CBG, cannabigerol; CBGV, cannabigivarin; THC, Δ⁹-tetrahydrocannabinol; THCV, propyl analogue of THC or tetrahydrocannabivarin.