Figure 5.

Top panel: representative CB₂ receptor-immunostained sections of the substantia nigra of rats unilaterally injected with 6-hydroxydopamine. Scale bar = 100 µm. CB₂ receptor–positive cells are indicated with arrows. Bottom panel: tyrosine hydroxylase immunostaining measured in the substantia nigra of CB₂ receptor–deficient and wild-type mice unilaterally injected with 6-hydroxydopamine. Values are means ± SEM (n = 5–6 mice per group) and are expressed as % of immunoreactivity in the lesioned side versus the non-lesioned side in the same animal. Data were subjected to Student's t-test.