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Cannabidiol (CBD) reduces the MOG-induced axonal damage in spinal cords of EAE mice. Mice were killed 30 days after EAE disease induction and sections of spinal cord were analysed for damaged axons using SMI-32 antibody. (A) MOG-induced EAE mice; (B) MOG-induced EAE mice treated with CBD (as described in Figure 1). Scale bar represents 200 µm.
