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. 2011 Aug;163(7):1507–1519. doi: 10.1111/j.1476-5381.2011.01379.x

Figure 6.

Figure 6

Cannabidiol (CBD) reduces the MOG-up-regulated Iba-1 expression in spinal cords of mice. Representative pictures showing that (A) MOG injections increase Iba-1 staining in spinal cord, and (B) that CBD injections significantly decrease the level of Iba-1 staining. (C) Quantification of Iba-1 fluorescence in sections of control (Ctrl) and of EAE mice with and without CBD treatment. The results are presented as mean ± SEM of total fluorescence from 8–11 spinal fragments from three to four mice per each experimental group. One-way anovaF(3,37) = 30.23, P < 0.0001, followed by Bonferroni post hoc test. *P < 0.001 versus Ctrl. #P < 0.001 versus EAE mice. Scale bar represents 100 µm.