Figure 7.

Structure/function analysis of HMG boxes. HMG boxes are indicated as open box and labeled. Bold lines indicate the acidic tail. All constructs contain additional 1-kb upstream and 1-kb downstream genomic sequences. (a) Constructs were tested in wild-type background for any dominant-negative or gain-of-function effect. (b) Constructs were tested in son-1(sy549) mutant background for any rescuing activity. The number of transgenic lines tested in which >75% of the animals showed wild-type SPD marker expression is indicated; these were considered positive for rescuing activity. (+) Positive for tested activity; (−) negative for tested activity.